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Eclipse 2000 HMB or Beta-hydroxy-metylbutyrate is produced in the body from proteins containing the amino acid Leucine. HMB’s effects on muscle metabolism were discovered and patented by scientists at Iowa State University and Vanderbilt University. HMB may increase the strengthening effects of exercise by minimizing the muscle tissue breakdown that occurs after strenuous activity. This enables the body to speed up the muscle building process and gain significantly more strength. Sold under U.S. Patent # 5,348,979.
HMB (beta-hydroxy betamethylbutyrate) is a metabolite of the amino acid leucine. HMB has been theorized to increase strength and muscle by preventing post workout muscle breakdown(1). Scientists think HMB does this by acting as a precursor to muscle that supports repair. Muscle growth is then assisted by having extra substrate for membrane growth, thus having a rapid return to increase protein synthesis(2, 3).
It appears that 3 grams divided throughout the day is the best dosing pattern for athletes weighing 200 lbs. or less. This 3 gram dose achieved the best strength and muscle gains for athletes in the above weight category. Athletes weighing more than 200 lbs. may receive enhanced benefits by using 4 to 6 grams per day. This dosing pattern works best when taken 3 times per day with the largest dose 1 to 2 hours pre-workout. Eclipse has designed a 750-mg capsule. Just 1 cap in the morning, 1 at midday, and 2 pre-workout makes Eclipse’s HMB the most convenient method of HMB consumption.
The current research does not suggest cycling or stopping HMB. Continual intake will maintain any muscle gains and has been shown to be safe at the recommended doses. Some research even shows benefit for endurance athletes by improving aerobic endurance(4).
HMB can be used by a wide range of athletes and should be considered an essential supplement. Other Ingredients: Dicalcium Phosphate and Magnesium Stearate. Nutritional uses of HMB are licensed to Metabolic Technologies Incorporated under U.S. Patent #5,348,979.
REFERENCES
1. Nissen S. 1996. Effects of leucine metabolite beta-hydroxy-beta methylbutyrate on muscle metabolism during resistance exercising training. J. Appl. Physiol. Nov; 81(5): p. 2095-2104.
2. Nissen S; et al. 1996. Effects of beta-hydroxybeta methylbutyrate Supplementation on strength and body composition of trained and untrained males during intense resistance training. FASCB J. 10(3): A287.
3. Nissen S; et al. 1997. Effect of feeding beta-hydroxy-beta methylbutyrate on body composition and strength of women. FASEB J. 11:150.
4. Vukovich M. et al. 1997. Effect of betahydroxy-beta methylbutyrate Supplementation on VO2 peak and maximal lactate in endurance trained cyclist. Med. Sci. Sports Exerc. 29(5): 5252.
HMB Nutritional Facts
Serving Size: 1 Capsule
Servings Per Container:
120 capsule container has 120 servingsIngredients Per 1
CapsuleHMB (Beta-hydroxy-metylbutyrate) 750 mg Other HMB Ingredients: Dicalcium Phosphate and Magnesium Stearate
Recommended Dosage: As a dietary supplement, take 4 capsules divided throughout the day with your largest dose (2 capsules) pre workout.