Eclipse Glutamine
Powder, One of the most effective anti-catabolic supplements available now
in pure free form powder. Glutamine
Powder Glutamine has an important
structural role, comprising 5-10% of amino acid residues in various proteins.
Glutamine is a major vehicle for the transfer of nitrogen between tissues.
Maximum growth and proliferation of most cell types occur with adequate
glutamine stores. Dependence on glutamine for cellular growth and function has
been clearly demonstrated for intestinal mucosal cells and cells of the immune
system.(1) Most glutamine is partly metabolized to form alanine and
lactate. During fever, surgery, and trauma muscle free glutamine concentrations
fall. Adequate circulating glutamine is needed for mucosal healing and muscle
protein synthesis; therefore glutamine may be considered “conditionally
essential.” Studies suggest that providing increased oral protein intake can
replete muscle glutamine concentrations.(2) Extensive animal
studies have demonstrated that declining glutamine levels are correlated with
negative nitrogen balance, decreased rates of protein synthesis and increased
protein degradation. Therefore, the provision of glutamine might have anabolic
effects leading to improved tissue function. The potential therapeutic use of
glutamine as a nutrient in human beings has been investigated in several recent
studies. All of these studies compared nitrogen balance and all found that the
groups that received glutamine via TPN had greatly improved nitrogen balance. Glutamine is anti-catabolic because it may spare muscle tissue during
stress. This means if you’re a natural body builder, subjecting yourself to a
certain amount of stress, the body responds by producing cortisol. The cortisol
then proceeds to breakdown muscle tissue. This is one of the reasons why natural
body builders have a difficult time making muscular gains. So supplementing with
glutamine would then impart muscle sparing. In time the muscle that would have
been lost is still there and eventually will add up to muscular gains. The main difference is
that the bodybuilder is performing heavy resistance type training in order to
spare muscle mass. Glutamine is more important to the dieting bodybuilder due to
its anti-catabolic and muscle sparing properties. Glutamine supplements during a
dieting phase may cause muscle sparing and fullness due to cellular volumizing. Glutamine
Powder Nutritional Facts Serving Size: 1
heaping teaspoon Recommended
Dosage: As a dietary supplement, take one teaspoon daily or as directed
by a health professional or trainer. Glutamine has no taste readily dissolves in
water or when mixed with your favorite beverages.
Caution:
Do Not Give To Children Under 12 Years of Age.
The Anti-Catabolic Nutrient
Glutamine plays a key part with the branched chain amino acids (BCAA) in muscle
energy metabolism and the over training syndrome of athletes. Approximately, 55%
of glutamine taken up is oxidized via alpha-ketogluterate and the Kreb’s cycle
to form CO2 and a further 20% is incorporated into citrate, lactate, organic
acids, and glucose.
The relative mild stress of weight training can result in a significant decline
in skeletal muscle free glutamine.(3) Over training is associated with even
greater decreases in muscle glutamine and to somewhat lesser extent plasma
glutamine concentrations.(4) There is a higher rate of glutamine synthesis and
release in skeletal muscle in catabolic or weight loss states.
A large body of data in experimental animals and increasing data in human beings
indicate that glutamine supplemented nutrition can have significant therapeutic
benefit in the management of catabolic disease states.
What we have established is that glutamine is an anti-catabolic nutrient and
secondly that glutamine should be one of the essential or indispensable amino
acids.
Another aspect of glutamine would be during the contest phase of bodybuilding.
This phase includes the stress of training coupled by the stress of the
pre-contest diet i.e. hypocaloric intake. The dieting bodybuilder is similar in
comparison to the malnourished or hypermetabolic patient.
The exact amount of glutamine needed by bodybuilders has not been scientifically
established. The current data indicates ingesting 5-10 grams per day. It would
also make sense to load on glutamine with 20 grams or 4 tsp. divided throughout
the day for 5 days then maintain glutamine stores with 5-10 grams per day.
Glutamine should not only be considered a conditionally essential amino acid but
also a conditionally essential bodybuilding supplement.
REFERENCES
1. Wagenmakers, AJ. 1998. “Muscle amino acid metabolism at rest and during
exercise: role in human physiology and metabolism”. Exer Sport
Sci Rev; 26:p. 287-314.
2. Kingsbury, KJ. et al. 1998. “Contrasting plasma free amino acid patterns in
elite athletes: association with fatigue and infection”. Br J Sports Med. Mar;
32(1):p. 25-32.
3. Mero, A. et al. 1997.”Leucine supplementation and serum amino acids,
testosterone, cortisol and growth hormone in male power athletes during
training”. J Sports Med Phys Fitness. June; 37(2):p. 137-145.
4. Rowbottom, D.G. et al. 1996.”The emerging role of glutamine as an indicator
of exercise stress and overtraining”. Sports Med. Feb; 21(2):p. 80-97.
Servings Per Container:
250 gram container has 50 servings
1000 gram container has 200 servings
Ingredient
Per 1
Heaping teaspoon
L-Glutamine
5
g